We retrospectively examined 175 situations of radical resection of cancer of the colon aged 75 many years or older performed in our department from January 2000 to December 2014. There were 133/29/11/2 customers for PS 0/1/2/3, respectively. The median CCI was 4.0(range 1-11). When you look at the multivariate analysis for overall survival(OS), there clearly was a big change in PS, BMI, N-factor, venous intrusion, pathological stage, neutrophil-to-lymphocyte rate (NLR), lymphocyte-to-monocyte rate(LMR), and modified Glasgow prognostic scale(mGPS). When you look at the multivariate analysis for relapse-free survival(RFS), there clearly was a big change in gender, T-factor, N-factor, pathological stage, collected lymph nodes, NLR, LMR, and mGPS. It had been suggested that their preoperative basic and health conditions can lead to the good oncologic outcomes when it comes to senior customers in colon cancer.We examined the consequence of chemoradiotherapy(CRT)on pancreatic cancer and also the significance of preoperative chemoradiotherapy( NACRT)on resectable pancreatic cancer. The subjects were 36 customers who underwent CRT for locally advanced pancreatic cancer tumors experienced in our division in past times 12 years(. 1)Regarding the antitumor aftereffect of CRT, cyst diameter, cyst marker, and FDG for PET assessment had been reduced in 72per cent, 81%, and 96% of situations, respectively. In inclusion, the effect of Grade 1b plus 2 had been seen in 10 of 16 patients who had been resected after CRT(response price 63%). In these successful situations, irradiation of 40 Gy or even more and oral administration of S-1 1,500 mg or maybe more were performed during this time period. In inclusion, the survival rate associated with the NACRT plus S group(16 cases)was exactly like that of the SF group (20 situations)of cStage ⅡA or lower at the same time, 50% success ended up being longer, and regional recurrence was less. On the basis of the above, preoperative chemoradiotherapy combined with S-1 for resectable pancreatic cancer tumors is a promising preoperative treatment in the future.Stage Ⅳ gastric cancer(GC)with ovarian metastasis showed bad prognosis and its particular treatment strategy stays confusing. Recent scientific studies identified the good prognostic effect of conversion surgery in Stage Ⅳ GC after intensive chemotherapy. We report here a case with advanced level GC and ovarian metastasis, just who underwent transformation surgery for all of them followed by Cholestasis intrahepatic chemotherapy and had a long-term success. We evaluated the literatures in order to discuss clinical need for our treatment strategy.The client ended up being a 57-year-old male. He was diagnosed with locally advanced rectal cancer infiltrating the left levator ani muscle mass. Chemotherapy(S-1 plus L-OHP plus bevacizumab regimen)was began for the purpose of acquiring a negative circumferential radial margin. Following the 2nd course, he presented with perforation regarding the sigmoid colon which is why an urgent situation procedure ended up being done. The perforation had been located 5 centimeters over the cyst in the sigmoid colon. We performed limited resection associated with sigmoid colon to repair the perforation and produce a sigmoid colostomy. CT, after the first S-1 plus L-OHP plus bevacizumab chemotherapy regimen, revealed cyst shrinking. Following 2 more classes Immune landscape of chemotherapy( S-1 plus L-OHP program), we performed transanal total mesenteric excision(taTME)as curative surgery. R0 resection was achieved. The combined transanal and laparoscopic approach was highly effective for a patient with pan-peritonitis.In the last few years, stenting and stoma creation as a bridge to surgery for obstructive left-sided cancer of the colon have now been attracting attention. All of us has a stent-independent method and executes primary CCG-203971 price resection after stoma building and preoperative chemotherapy with cT4 customers. In this study, we investigated both its credibility and issues. Sixty-five cases of scope-impassable left-sided a cancerous colon surgeries from November 2015 to September 2020 were included. The short- and long-lasting results had been examined in Stage Ⅱ-Ⅲ and Ⅳ. The median time from entry to surgery ended up being 6 days and 8 times, correspondingly; postoperative morbidity had been 9.5% and 17.4%, correspondingly; anastomotic leakage had been 4.8% and 17.4%, respectively; permanent stoma had been 26.2% and 21.7%, correspondingly; and postoperative demise was zero both in groups. In group Ⅱ-Ⅲ, the 3-year general survival rate was 77.0%, 3-year disease-free success price was 72.7%, plus in group Ⅳ, the 3-year general success rate was 36.0%. Regional recurrence had been noticed in 2(16.7%)of 12 patients with cT3-4N+ rectosigmoid cancer just who failed to get neoadjuvant chemotherapy. The stent-independent strategy had been safe with reasonable morbidity, therefore the permanent stoma rate was reasonable.We report 4 situations of liver metastasis from renal cellular carcinoma(RCC). Case 1 72 yrs . old, female. Pancreatic metastasis had been resected 7 years after resection of left RCC, and hepatic posterior sectionectomy ended up being performed for several liver metastases 2 years later on. After that, multi-organ metastasis appeared and she died regarding the main condition. Situation 2 72 yrs old, male. Liver metastasis and right RCC appeared 16 years after resection of remaining RCC, and hepatic posterior sectionectomy and partial resection of correct kidney had been done. Nine months later on, liver metastasis recurred and hepatic limited resection had been done. Instance 3 55 yrs . old, male. After surgery for right RCC with tumor thrombus into the right atrium, multiple lung and liver metastases appeared, and hepatic main bisectionectomy ended up being performed after chemotherapy. Case 4 60 yrs old, male. Numerous pancreatic and lung metastases appeared ten years after resection of left RCC, & most of them shrank or disappeared with chemotherapy. But increasing metastases starred in the tail of pancreas additionally the right lobe of liver 16 months later on, and hepatic subsegmentectomy and distal pancreatectomy had been done.