Gastroscopy revealed a 15-mm ulcerative lesion(Type 0-Ⅱc plus Ⅲ)on the more curvature associated with the top gastric body. Tumefaction biopsy revealed well-differentiated adenocarcinoma. The patient was suspected of deep submucosal intrusion as a result of poor stretching associated with gastric wall surface therefore the ulcer level; hence, he had been used in Tumor biomarker our medical center for surgery. Whenever gastroscopy had been duplicated, the ulcer had been found is scarred(Type 0-Ⅱc), thereby showing the event of intramucosal carcinoma; therefore, endoscopic submucosal dissection had been performed. The pathological finding showed 10×6 mm, tub1, pT1a, ly0, v0, pUL1, pHM0, pVM0, suggesting a curative resection. Early gastric cancer for the despondent type is well known to build up a malignant cycle with repeated improvements and exacerbations for the ulcer. Diagnosing the level of cyst intrusion is especially hard when there is an energetic ulcer. For tiny lesions with active ulcers, repeating gastroscopy might provide for correct analysis and proper treatment.This case relates to a 72-year-old man whom went to the crisis division with a complaint of upper abdominal discomfort. On assessment, we suspected gastric perforation due to gastric cancer and decided to do disaster surgery. We performed laparoscopic omentoplasty and collected #4d lymph nodes which were enlarged on CT. The pathological diagnosis was lymph node metastasis. Considering CT conclusions, we determined it had been Bulky N. For initial administration, we performed 3 preoperative chemotherapy(SOX therapy)courses and staging laparoscopy. On surgery, considerable disseminated nodules in the stomach wall, stomach wall, and liver surface had been found, and ascites cytology uncovered good findings. Therefore, we would not do major lesion resection. Although the disseminated nodule failed to pathologically show tumor cells, CY1 had been found, bringing on an analysis of unresectable gastric disease. Since the tumor ended up being HER2 3+, we started SOX/trastuzumab treatment. After 16 programs, staging laparoscopy had been performed as the lymph nodes had shrunk dramatically. The outcome revealed no cyst cells in ascites together with disseminated nodules, and laparoscopic total gastrectomy ended up being later done. Pathological findings showed no cyst cells into the primary lesion or lymph nodes; consequently, a diagnosis of pathological full response had been made. Presently, the in-patient is alive without recurrence for a few months after surgery.As shown when you look at the ATTRACTION-2 trial, nivolumab works well as third-line chemotherapy for advanced or recurrent gastric cancer and esophagogastric junction cancer. We report someone with esophagogastric junction disease which underwent conversion surgery after third-line chemotherapy with nivolumab. The individual was a 72-year-old lady. Upper gastrointestinal endoscopy unveiled advanced esophagogastric junction cancer tumors of Siewert type Ⅱ, and computed tomography revealed multiple hepatic and pulmonary metastases. The esophagogastric junction cancer tumors had been see more diagnosed as cT3N1M1, cStage Ⅳb, and she ended up being administered SP as first-line and nab-PTX/RAM as second-line treatment, but modern infection stayed. Nivolumab as a third-line treatment extremely reduced the hepatic and pulmonary metastases as a result of its management had been initiated, and transformation surgery was done after 28 programs. The pathological diagnosis was ypT1b2(SM2), ypN0. After discharge through the hospital, postoperative chemotherapy with nivolumab had been proceeded into the outpatient center, and there has been no proof of infection progression.A 62-year-old man underwent radical surgery to treat remnant gastric cancer with mesojejunal lymph node metastasis. Based on the fifteenth edition associated with Japanese Gastric Cancer Association, a histological diagnosis of B-35-A, kind 3, tub2>tub1, pT3(SS), pN3a(10/37), cM0, CY0, pStage ⅢB was made. All lymph node metastases had been recognized when you look at the mesojejunum. Adjuvant chemotherapy with S-1 plus docetaxel was started after 4 weeks of surgery. The in-patient remains alive without recurrence after one year of surgery. Therefore, radical surgery with dissection of the mesojejunum and intensive adjuvant chemotherapy might improve prognosis in a remnant gastric disease patient with mesojejunal lymph node metastasis.A male patient in the seventies visited our hospital with a complaint of tarry feces. A detailed evaluation unveiled gastric cancer( pap, tub1, HER2[3+]), with several lungs and liver metastases. Chemotherapy with 4 courses of capecitabine, cisplatin, and trastuzumab(Tmab)and 4 classes of regular paclitaxel(wPTX)plus 3w-Tmab were administered, and CR was achieved. Thereafter, Tmab was administered alone; nevertheless, local recurrence associated with primary lesion ended up being seen 24 months after analysis, and treatment with PTX and Tmab ended up being resumed. After 68 months of diagnosis, the recurrent tumor increased in size. Therapy with nab-PTX plus ramucirumab was started, after which, the cyst growth was restricted. Sooner or later, the individual died of some other infection after 6 many years and 5 months of analysis. Chemotherapy for unresectable advanced/recurrent gastric cancer tumors has actually an extraordinary antitumor effect; nevertheless, a total cure with chemotherapy alone is hard. Consequently, a multimodal treatment, including chemotherapy, surgical treatment, and radiotherapy, is important.G-CSF producing esophageal carcinosarcoma is very unusual, and its effective therapy method remains undefined. Right here, we report the case of a 69-year-old woman who underwent successful two-stage surgery making use of mediastinoscopic esophagectomy and laparoscopic repair for the management of severe anemia, malnutrition, and irritation as a result of G-CSF making esophageal carcinosarcoma(G-CSF 265 pg/mL). Chemoradiotherapy could not manage lymph node recurrences into the client; nevertheless, nivolumab was discovered to be effective and aided achieved a prolonged limited response.Mediastinoscopic esophagectomy(ME)is a minimally unpleasant strategy without thoracotomy and pulmonary atelectasis during surgery. Here, we report the case of a 67-year-old patient who was simply effectively treated with thoracic esophageal cancer and severe persistent pulmonary infection hepatic toxicity utilizing ME and house enteral nutrition treatment.